Conference Program
6 September – Pre-Conference excursion – get-together
13:30–16:00
THE VIKING MUSEUM LADBY
Vikingevej 123, 5300 Kerteminde
Followed with dinner at Great Northern Resort on the beach
(Speakers are invited; participants are welcome to join and pay themselves)
7 September – Day 1:
Epigenetic Foundations of Neural Fate
08:00–09:30
Registration and Coffee
09:30–10:00
Welcome by the Organizers
Session 1:
Chromatin Dynamics in Early Neural Development
10:00–10:30
Histone Modifying Enzymes Contribute to the Establishment and Maintenance of Neuronal Identity
Boyan Bonev
10:30–11:00
The Establishment of Neuron-Type Identities and Enhancer Selectivity
Nuria Flames
11:00–11:10
Early cortical fate decisions predict divergent outcomes among ASD risk genes
Elad Dvir et al
11:10–11:20
Nuclear Myosin 1 Regulates Neuronal Maturation Through Chromatin Remodeling of Developmental Gene Programs
Valentina Fambri, et al
11:20–11:30
Regulation of neural stem cell fate and brain development by the lipid phosphatase OCRL
Raghu Padinjat et al
11:30–13:00
Lunch Break + Informal Discussions
Session 2:
DNA Methylation and Lineage Restriction
13:00–13:30
Epigenetic Control in Oligodendrocyte Lineage
Gonçalo Castelo-Branco
13:30–14:00
Epigenetic Timing in Neurogenesis
Yukiko Gotoh
14:00–14:10
DNA methylation and neurodevelopmental disorders
Anna Starnawska
14:10–14:20
MicroRNAs are required within a critical time window to define neural patterning during early human brain development
Cledi Alicia Cerda-Jara, et al
14:20–14:30
Patient-Derived Air-Liquid Interface Forebrain Organoids Reveal Functional Synaptic Deficits in Schizophrenia
Pia Jensen, et al
14:30–15:00
Coffee Break
Session 3:
3D Genome Architecture in Neural Lineage Specification
15:00–15:30
Regulatory Role of Chromatin Conformation in Neural Cells
Ana Pombo
15:30–16:00
TBA
Sebastian Holst
16:00–16:10
Steering Transcription Factor Activity during Cortical Development
Arun Mariappan
16:10–16:20
Chromatin priming and Phox2b co-factor shape the neuronal response to ASCL1 in pluripotency
Roberta Azzarelli
Session 4:
Mechanisms of Neural Fate Maintenance
16:20–16:50
Epigenetic Control of Neuronal Identity Maintenance
Angel Barco
16:50–17:20
Terminal Selectors and Maintenance of Meuronal Identity
Oliver Hobert
17:20–17:50
Balance between Neuronal Differentiation and Maintenance
Carmen Birchmeier-Kohler
17:50–18:00
tbatb
Taro Kitazawa
Whole-genome single-cell multimodal molecular recording reveals cell identity transitions
18:00–18:10
Ascl1 coordinates temporal transcriptional programs during neurogenesis through differential cis-regulatory element engagement and cooperation with Notch signalling
Diogo S. Castro, et al
18:10–18:20
An integrative network-based analysis on human neurodevelopment reveals key regulatory genes and pathways crosstalk
Francesca De Beni, et al
18:20–18:30
Enhancer turnover underlies divergent cortical expression across mouse and human development
Darina Abaffyová, et al
18:30–19:30
Poster Session 1 (Odd Numbers) + Informal Discussions
19:30–21:30
Gala Dinner + Meet the Speakers
21:30–23:00
Night Party with DJ Thomas Kjærholt,
8 September – Day 2:
Emerging Tools to Decode and Manipulate Neural Fate
08:00–08:30
Opening of Day 2 by the Organizers
Session 5:
Evolution of Regulatory Programs in Neural Systems
08:30–09:00
Cortical Development and Neuronal Identity
Victor Borrell
09:00–09:30
Mechanisms of O-GlcNAc signalling in neurodevelopment
Daan van Aalten
09:30–10:00
Early neurodevelopment phenotypes in autism spectrum disorders
Gaia Novarino
10:00–10:30
Deciphering Gene Regulatory Circuitry Underlying Cranial Neural Crest Fate Decisions
Tatjana Sauka-Spengler
10:30–10:40
Nuclear actin-dependent regulation of hnRNPU chromatin binding links MARs-associated genome organization to neurogenic transcriptional programs
Nadine Hosny El Said, et al
10:40–10:50
From dysregulation to reprogramming: regulation-informed validation of transcription-factor rescue in ADNP-mutant human cortical organoids
Alessandro Vitriolo, et al
10:50–11:30
Coffee Break
11:30–12:00
TBA
Jürgen Knoblich
12:00–12:30
Single-Cell Transcriptomics and RNA Regulation in the Brain
Nikolaus Rajewsky
12:30–13:00
Neural Progenitor Dynamics at Single-Cell Level
Daniel Lim
13:00–14:00
Lunch Break
Session 6:
Transcriptional Misregulation in Neural Disorders
14:00–14:30
ASD and Transcriptional Dysregulation
Daniel Geschwind
14:30–15:00
Disruption of Gene Regulatory Networks in Neurodevelopmental Disorders
Vijay Tiwari
15:00–15:30
Genetics of psychiatric disorders
Ditte Demontis
15:30–16:00
Transcriptional Control and Enhancer Architecture
Aleksandra Pekowska
16:00–17:30
Poster Session 2 (Even Numbers) + Informal Discussions
19:00–21:30
Dinner in Odense at Sortebro Kro- Participants find dinner for themselves
9 September – Day 3:
Neural Fate Maintenance Failure and Therapeutic Reprogramming
08:00–08:30
Opening of Day 3 by the Organizers
Session 7:
3D Genome Architecture in Neural Lineage Specification
08:30–09:00
Nuclear β-Actin Couples Chromatin Architecture, Matrix Mechanics and Neural Cell Fate
Piergiorgio Percipalle
09:00–09:30
Maintenance of Adult Neurogenesis
Hongjun Song
09:30–10:00
Cell-type Classification, Scalable Gene Expression Tools
Hongkui Zeng
10:00–10:10
CTCF dosage sets the tempo of neural fate acquisition in the developing forebrain
Alireza Ghahramani, et al
10:10–10:20
Deciphering the regulatory roles of BRD4 on 3D chromatin structure in human ESCs and neuronal lineages?
Ziba Shadman, et al
10:20–10:50
Coffee Break
Session 8:
Mechanisms of Neural Fate Maintenance
10:50–11:20
Synaptic and Circuit Plasticity in Aging
Yinxi Lin
11:20–11:50
Stem Cell Fate and Long-Term Neural Identity
Magdalena Goetz
11:50–12:20
Neural Stem Cell Regulation and Niche Signals
Fiona Doetsch
12:20–12:50
Intrinsically Disordered Proteins and Neural Identity
Xavier Salvatella
12:50–13:00
Best Short Talk and Best Poster Awards
13:00–14:10
Concluding Remarks by the Organizers
13:10–14:10
Takeaway Lunchsnack for participants, Speakers lunch separately
9 September – Post Conference Excursion
15:00–17:00
Hans Christian Andersens House
H.C. Andersen Haven 1
5000 Odense C
(Speakers are invited; participants are welcome to join and pay themselves)